RT Journal
A1 Klein BK, Klein R
T1 FOrecasting age-related macular degeneration through 2050
JF JAMA
JO JAMA
YR 2009
FD May 27
VO 301
IS 20
SP 2152
OP 2153
DO 10.1001/jama.2009.729
UL http://dx.doi.org/10.1001/jama.2009.729
AB 
Age-related macular degeneration (AMD) is an insidious process that increases in prevalence and severity predictably with age. The end stage of this condition causes profound loss of central vision. In the Beaver Dam Eye Study, in persons who were aged 75 years or older, the 15-year cumulative incidence of early stage AMD in the more severely involved eye was 24% and of late stage AMD it was 8%.1 In that study, more than 52% of eyes with incident severe loss of vision (20/200 or poorer) had late-stage AMD.2