RT Journal A1 Colman E T1 THe metabolic syndrome and obesity JF JAMA JO JAMA YR 2009 FD April 15 VO 301 IS 15 SP 1602 OP 1608 DO 10.1001/jama.2009.562 UL http://dx.doi.org/10.1001/jama.2009.562 AB During the past 5 decades, unhealthy degrees of adiposity have been variously characterized as overweight, moderate overweight, severe overweight, unhealthy weight, preobese, obese, and extreme obesity. The National Heart, Lung, and Blood Institute currently defines obesity as a body mass index (BMI) greater than 30 (calculated as weight in kilograms divided by height in meters squared). Individuals with a BMI of 25 to 29.9 are considered overweight. Throughout his book, Bray uses “overweight” to describe the condition he previously called “obese” (ie, BMI >30) and uses “clinically overweight” to describe individuals with weight-related comorbid conditions. He opts for the new terminology out of deference to patients who consider the word “obese” pejorative. In this review, I adhere to the National Heart, Lung, and Blood Institute definitions of overweight and obesity.