RT Journal
A1 Friedrich MJ
T1 CAncer drug target?
JF JAMA
JO JAMA
YR 2009
FD February 4
VO 301
IS 5
SP 477
OP 477
DO 10.1001/jama.2009.41
UL http://dx.doi.org/10.1001/jama.2009.41
AB 
In studies in zebrafish embryos, the researchers identified a DNA demethylation process that involves the coupling of these 2 enzymes and a nonenzymatic factor. Defects in DNA methylation, a cellular process that shuts off genes that either aren't needed or are malfunctioning, can lead to the development of cancer and other diseases.