RT Journal
A1 Bach PB
T1 SMoking as a factor in causing lung cancer
JF JAMA
JO JAMA
YR 2009
FD February 4
VO 301
IS 5
SP 539
OP 541
DO 10.1001/jama.2009.57
UL http://dx.doi.org/10.1001/jama.2009.57
AB 
In 1950, when Wynder and Graham1 published their landmark article in JAMA about the link between smoking and lung cancer, the lung cancer mortality rate for men in the United States had already experienced a more than 4-fold increase over the prior 3 decades, and appeared likely to surpass cancers of the colon and rectum as the leading cause of cancer death among men.2 The increase paralleled the rise in cigarette consumption among men that had occurred roughly 20 years earlier.