RT Journal
A1 Corey L
T1 CDc recommendations for opt-out hiv testing
JF JAMA
JO JAMA
YR 2009
FD January 21
VO 301
IS 3
SP 274
OP 276
DO 10.1001/jama.2008.1008
UL http://dx.doi.org/10.1001/jama.2008.1008
AB 
To the Editor: I endorse the CDC recommendations for opt-out HIV testing discussed in the Special Communication by Dr Bartlett and colleagues1 and believe that all available tools to identify and counsel HIV-infected individuals should be pursued. However, one important population of persons must be considered in any such policy: those who are participants in HIV vaccine trials. By 2008, more than 30 000 individuals worldwide had participated voluntarily in experimental HIV vaccine trials.2- 3 The CDC recommendations pose some complex issues for these HIV vaccine trial participants, as many will test positive in many of the antibody-based screening assays.4 In the last 5 years, almost all HIV vaccines have elicited some reactivity in commercially based assays.4 All of these vaccine study participants are HIV-negative by RNA/DNA assays.2,5