RT Journal
A1 Hampton T
T1 HIv and the brain
JF JAMA
JO JAMA
YR 2008
FD August 6
VO 300
IS 5
SP 496
OP 496
DO 10.1001/jama.300.5.496-d
UL http://dx.doi.org/10.1001/jama.300.5.496-d
AB 
Investigators at the Scripps Research Institute in La Jolla, Calif, used metabolomic approaches to study rhesus macaques with central nervous system disease caused by simian immunodeficiency virus. During infection, they found increases in the cerebrospinal fluid of certain metabolites, including carnitine, acyl-carnitines, fatty acids, and phospholipid molecules, that correlated with increased expression of specific phospholipases in the brain.