RT Journal
A1 Pickhardt PJ, Levin B, Bond JH
T1 SCreening for nonpolypoid colorectal neoplasms
JF JAMA
JO JAMA
YR 2008
FD June 18
VO 299
IS 23
SP 2743
OP 2744
DO 10.1001/jama.299.23.2743-a
UL http://dx.doi.org/10.1001/jama.299.23.2743-a
AB 
The terminology is unclear. A distinction must be made between the relatively flat lesions described in this study (defined as elevated lesions with a height less than half the diameter) and completely flat or depressed lesions. The authors note that “completely flat lesions are exceedingly rare” and were presumably absent in this study. Depressed lesions comprised less than 1% of all colorectal lesions (18/2770), only 4 of which were seen at screening. Therefore, nearly all nonpolypoid lesions were elevated from the surrounding mucosa, which is a critical distinction favoring detection at both standard colonoscopy and computed tomographic (CT) colonography.