RT Journal A1 DeAngelis CD, Fontanarosa PB T1 Impugning the integrity of medical science: The adverse effects of industry influence JF JAMA JO JAMA YR 2008 FD April 16 VO 299 IS 15 SP 1833 OP 1835 DO 10.1001/jama.299.15.1833 UL http://dx.doi.org/10.1001/jama.299.15.1833 AB Two articles1- 2 in this issue of JAMA provide a glimpse of one company's apparent misrepresentation of research data and its manipulation of clinical research articles and clinical reviews; such information and articles influence the education and clinical practice of physicians and other health professionals. The direct influence of for-profit companies on education3- 6 and clinical practice7- 8 has been well documented, so this Editorial deals primarily with clinical research.