RT Journal A1 Offit K T1 Genomic profiles for disease risk: Predictive or premature? JF JAMA JO JAMA YR 2008 FD March 19 VO 299 IS 11 SP 1353 OP 1355 DO 10.1001/jama.299.11.1353 UL http://dx.doi.org/10.1001/jama.299.11.1353 AB There has been a recent explosion of commercial availability of genomic “tests” for diseases, conditions, traits, and ancestry. Dozens of companies advertise their services directly to consumers who, if they are willing to provide a DNA sample (usually from saliva) and are also willing to pay the charges, can obtain genetic information about various health conditions. These “conditions” range from the tendency to form wet vs dry earwax to risk for significant adult-onset diseases (Table).1