RT Journal
A1 Mets OM, de Jong PA, Prokop M
T1 EValuating other diseases with computed tomographic screening for lung cancer—reply
JF JAMA
JO JAMA
YR 2013
FD February 20
VO 309
IS 7
SP 655
OP 656
DO 10.1001/jama.2012.157211
UL http://dx.doi.org/10.1001/jama.2012.157211
AB 
In Reply: The comments by Dr Huesch and colleagues and Dr Wittig address important concerns about screening in smokers and the technical limitations of CT. Screening in current and former smokers is challenging because smoking cessation is the most effective tool for risk reduction, be it cancer risk, cardiovascular risk, or progression of COPD. This potentially makes a negative outcome of screening counterproductive because it might be viewed as an incentive to continue smoking. However, smoking cessation remains difficult in any setting. Adherence is low and the outcome of screening has little long-term influence on smoking behavior.1