RT Journal A1 Schuetz P, Briel M, Mueller B T1 CLinical outcomes associated with procalcitonin algorithms to guide antibiotic therapy in respiratory tract infections JF JAMA JO JAMA YR 2013 FD February 20 VO 309 IS 7 SP 717 OP 718 DO 10.1001/jama.2013.697 UL http://dx.doi.org/10.1001/jama.2013.697 AB Clinical Question  In patients with respiratory tract infection, is measurement of procalcitonin to guide antibiotic prescriptions associated with reduced antibiotic exposure without increases in all-cause mortality or treatment failure?Bottom Line  The measurement of procalcitonin to guide initiation and duration of antibiotic treatment in patients with respiratory tract infections of varying severity is associated with lower antibiotic exposure without increasing all-cause mortality or treatment failure.