RT Journal A1 Shang C T1 Β-blocker use for patients with or at risk for coronary artery disease JF JAMA JO JAMA YR 2013 FD February 6 VO 309 IS 5 SP 438 OP 438 DO 10.1001/jama.2012.128869 UL http://dx.doi.org/10.1001/jama.2012.128869 AB To the Editor: It is unfortunate that the observational study on β-blocker use and clinical outcomes in stable outpatients did not distinguish different types of β-blockers.1 In a review of β-blockers for hypertension, three-quarters of participants in randomized controlled trials (RCTs) used atenolol.2 Atenolol has been shown repeatedly to be no better than placebo in improving clinical outcomes such as reduction of mortality and cardiovascular events in RCTs and meta-analyses.2- 3