RT Journal
A1 Czarnetzki C, Elia N, Tramèr MR
T1 BLeeding risk and dexamethasone use in children undergoing tonsillectomy
JF JAMA
JO JAMA
YR 2013
FD February 6
VO 309
IS 5
SP 437
OP 438
DO 10.1001/jama.2012.113510
UL http://dx.doi.org/10.1001/jama.2012.113510
AB 
Gallagher et al1 applied the same threshold of 5% to all bleeding end points (any bleeding, bleeding requiring rehospitalization, reoperation due to bleeding) to indicate noninferiority. We agree that an increase of 5% in level I bleeding (any bleeding) might not necessarily be of clinical relevance. However, an increase of 5% in level III bleeding (ie, those needing a reoperation) is quite different.