RT Journal A1 Min JK T1 NOninvasive approach to assess coronary artery stenoses and ischemia—reply JF JAMA JO JAMA YR 2013 FD January 16 VO 309 IS 3 SP 233 OP 236 DO 10.1001/jama.2012.157208 UL http://dx.doi.org/10.1001/jama.2012.157208 AB Drs Lessick and Aronson inquired as to blinded integration of FFR and CT, which was needed to avoid the possibility of selection bias for determining FFRCT. Because CT-based computational models provide a 3-dimensional FFRCT in all coronary vessels, comparison of FFRCT with FFR required overlay at the location of the sensor wire used to measure FFR. Model construction and FFRCT were uniformly complete prior to integration.1