RT Journal
A1 Sethi A, Singh M, Arora R
T1 OMega-3 fatty acid supplementation and cardiovascular disease events
JF JAMA
JO JAMA
YR 2013
FD January 2
VO 309
IS 1
SP 27
OP 27
DO 10.1001/jama.2012.116644
UL http://dx.doi.org/10.1001/jama.2012.116644
AB 
To the Editor: The meta-analysis by Dr Rizos and colleagues1 synthesized the available evidence on omega-3 PUFA supplementation to prevent adverse cardiovascular outcomes. In addition to conventional random-effects meta-analyses, subgroup analyses and meta-regressions were performed. No association with type of prevention (ie, mixed or secondary) or omega-3 dose was found, and the authors did not demonstrate a net benefit from omega-3 PUFA supplementation after 2007. However, the type of omega-3 PUFA supplements and co-administered medications were not adequately explored.