RT Journal A1 Sinha SK, Detsky AS T1 MEasure, promote, and reward mobility to prevent falls in older patients JF JAMA JO JAMA YR 2012 FD December 26 VO 308 IS 24 SP 2573 OP 2574 DO 10.1001/jama.2012.68313 UL http://dx.doi.org/10.1001/jama.2012.68313 AB The ability to maintain an upright posture and walk are crucial to human survival. Until the development and dissemination of mobility assistance devices over the last few centuries, once a person lost these abilities, death often followed. Movement and upright posture are also important in protecting the integrity of organ systems and body functions such as skin, coagulation homeostasis, and cardiovascular fitness. Humans have developed considerable redundancy to sustain movement while either standing upright or sitting in a mobility assistance device like a wheelchair. Injury to one part of the neuromusculoskeletal system is compensated by recruiting other parts of the body to preserve upward mobility. However, with increasing age and injury, maintaining upright posture and movement becomes increasingly difficult. Falls are a manifestation of this phenomenon, serving as identifiers of other geriatric syndromes such as frailty and polypharmacy.