RT Journal A1 Howland J, Rohsenow DJ T1 RIsks of energy drinks mixed with alcohol JF JAMA JO JAMA YR 2013 FD January 16 VO 309 IS 3 SP 245 OP 246 DO 10.1001/jama.2012.187978 UL http://dx.doi.org/10.1001/jama.2012.187978 AB Energy drinks contain caffeine and often other substances such as guarana (containing guaranine, similar to caffeine), taurine (an amino acid), and sugar derivatives. The primary active ingredient is caffeine, usually with 80 to 141 mg of caffeine per 8 oz (equivalent to a 5-oz cup of coffee or 2 cans of soda).