RT Journal A1 Starr LM, Braslow A, Bircher N T1 PRevention of patient harm JF JAMA JO JAMA YR 2012 FD December 19 VO 308 IS 23 SP 2458 OP 2459 DO 10.1001/jama.2012.68799 UL http://dx.doi.org/10.1001/jama.2012.68799 AB To the Editor: The Viewpoint by Drs Pronovost and Bo-Linn1 on reducing patient harm “in the same way that engineers manage dynamic complexity: as a systems problem that requires an interdisciplinary systems solution” made 2 linked arguments. The first is that thinking analytically (ie, treating parts as both separate and independent) is “challenging, if not impossible” when faced with a systems problem. Analysis can usually quantify what is wrong but is frequently not useful to explain why. The better approach to a complex systems problem, including hospital-based medical harms, requires one to think systemically. The second argument is that thinking systemically means using systems-based methods that focus on interactions and integration.