RT Journal
A1 Punnoose AR, Lynm C, Golub RM
T1 ANtibiotic resistance
JF JAMA
JO JAMA
YR 2012
FD November 14
VO 308
IS 18
SP 1934
OP 1934
DO 10.1001/jama.2012.6916
UL http://dx.doi.org/10.1001/jama.2012.6916
AB 
Antibiotics  are compounds that can kill or interfere with the growth of microorganisms such as bacteria or viruses. Because antibiotics are often used unnecessarily or incorrectly, microorganisms have been able to adapt and survive. This is called antibiotic resistance . One way this happens is genetic mutations , which are random changes in genetic material that can be passed on from one virus or bacterium to successive generations. For example, penicillin is one of the oldest and most commonly used antibiotics. Some bacteria have developed an enzyme or protein that changes the structure of penicillin and prevents it from killing bacteria.