RT Journal A1 Sossai P, Sponga B T1 PHysical activity to combat depression in chronic heart failure JF JAMA JO JAMA YR 2012 FD November 7 VO 308 IS 17 SP 1738 OP 1739 DO 10.1001/jama.2012.14095 UL http://dx.doi.org/10.1001/jama.2012.14095 AB To the Editor: The article by Dr Blumenthal and colleagues1 regarding the effects of physical exercise on symptoms of depression in patients with chronic heart failure followed previous reports from the Heart Failure-A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) Investigators.2- 3 The primary aim of the multicenter, randomized controlled trial was to evaluate the efficacy and safety of physical exercise performed by patients with chronic heart disease.2