RT Journal
A1 Malani PN
T1 HArrison’s principles of internal medicine
JF JAMA
JO JAMA
YR 2012
FD November 7
VO 308
IS 17
SP 1813
OP 1814
DO 10.1001/jama.308.17.1813-b
UL http://dx.doi.org/10.1001/jama.308.17.1813-b
AB 
Medicine has evolved considerably during the 63 years since the first edition, and several entirely new specialties have emerged. As the editors recollect in the preface, “peptic ulcer disease was thought to be caused by stress, nearly every tumor that was not resected led to death, rheumatic heart disease was widely prevalent, and hepatitis B and [human immunodeficiency virus] infection were unknown.” Today, the sheer volume of information required by the internist is mind-boggling, and the body of evidence informing clinical care continues to burgeon. The transformation in how physicians learn the art and science of medicine has been equally dramatic.