RT Journal
A1 Markert JM
T1 THe role of early resection vs biopsy in the management of low-grade gliomas
JF JAMA
JO JAMA
YR 2012
FD November 14
VO 308
IS 18
SP 1918
OP 1919
DO 10.1001/jama.2012.14523
UL http://dx.doi.org/10.1001/jama.2012.14523
AB 
More problematic are the low-grade gliomas that occur in adults, referred to as grade II gliomas (LGGs). These tumors are characterized by an entirely different pattern of behavior. They are invasive and cannot be completely resected surgically; residual tumor cells are always present distal to the margin of resection no matter how extensive. Commonly, these tumors recur, eventually undergo malignant degeneration, and are ultimately fatal.1