RT Journal
A1 Friedrich MJ
T1 PRotective gene for malaria?
JF JAMA
JO JAMA
YR 2012
FD October 17
VO 308
IS 15
SP 1515
OP 1515
DO 10.1001/jama.2012.13775
UL http://dx.doi.org/10.1001/jama.2012.13775
AB 
The investigators performed genetic tests for the SAO defect in 1975 children from the Madang area of Papua New Guinea who were enrolled in 3 separate malaria studies: a clinical drug prevention trial with 1121 infants aged 3 to 21 months, a case-control study of 318 children with severe malaria aged 10 years and younger, and a treatment time-to-reinfection study of 206 children aged 5 to 14 years. In the 3 studies, the SAO genetic defect was associated with a reduction in risk of clinical P vivax episodes.