RT Journal
A1 Goodman DM, Burke AE, Livingston EH
T1 BLeeding disorders
JF JAMA
JO JAMA
YR 2012
FD October 10
VO 308
IS 14
SP 1492
OP 1492
DO 10.1001/jama.2012.4089
UL http://dx.doi.org/10.1001/jama.2012.4089
AB 
When tissues are injured, blood cell fragments called platelets  gather at the wound, providing a foundation for coagulation  (clotting). Platelets are bound together by a glue-like protein named von Willebrand factor. Once the initial platelet plug is built, clotting factors gather at the injury site to seal the wound, stop bleeding, and begin the healing process. The clotting factors work in a carefully timed sequence, resulting in a sturdy clot and healed wound.