RT Journal A1 Dodwell E, Snyder B, Wright J T1 OFf-label use of bone morphogenetic proteins in pediatric spinal arthrodesis JF JAMA JO JAMA YR 2012 FD October 10 VO 308 IS 14 SP 1429 OP 1432 DO 10.1001/jama.2012.12929 UL http://dx.doi.org/10.1001/jama.2012.12929 AB Bone morphogenetic proteins (BMPs) are approved for limited use in adults when healing may be suboptimal.2- 3 In addition to concerns about possible carcinogenesis, complications include wound dehiscence, spinal stenosis, and respiratory complications.4 The US Food and Drug Administration has not approved the use of BMPs in children.