RT Journal A1 Sibbing D, Hochholzer W, Kastrati A T1 INfluence of smoking on treatment with clopidogrel JF JAMA JO JAMA YR 2012 FD October 3 VO 308 IS 13 SP 1322 OP 1324 DO 10.1001/2012.jama.11187 UL http://dx.doi.org/10.1001/2012.jama.11187 AB Dr Gurbel and colleagues1 suggested in a Viewpoint that clopidogrel has a greater benefit in active smokers than in nonsmokers, explained by the enhancement of the antiplatelet action of clopidogrel by smoking. We want to highlight 2 aspects of the article.