RT Journal
A1 Rodwin MA, Abramson JD
T1 CLinical trial data as a public good
JF JAMA
JO JAMA
YR 2012
FD September 5
VO 308
IS 9
SP 871
OP 872
DO 10.1001/jama.2012.9661
UL http://dx.doi.org/10.1001/jama.2012.9661
AB 
Knowledge of the benefits and risks of prescription drugs is based mainly on published reports of clinical trials, yet the medical literature may present an incomplete and potentially biased sample of clinical trials.1 Trials with positive results generally are published more frequently than studies that conclude that a new drug poses greater risks or is no more effective than standard therapy or a placebo. Furthermore, some articles may distort trial findings by omitting important data or by modifying prespecified outcome measures. Lack of access to detailed information about clinical trials can undermine the integrity of medical knowledge.