RT Journal
A1 Kuehn BM
T1 EGg allergy treatment
JF JAMA
JO JAMA
YR 2012
FD August 22
VO 308
IS 8
SP 753
OP 753
DO 10.1001/2012.jama.10160
UL http://dx.doi.org/10.1001/2012.jama.10160
AB 
A team of researchers conducted a clinical trial of 55 children aged 5 to 11 years with an egg allergy to determine whether exposure to tiny amounts of egg over time might desensitize children to egg. This strategy has previously shown promise for individuals with peanut allergy (Burkes AW et al. N Engl J Med. doi: 10.1056/NEJMoa1200435 [published online July 19, 2012]). The children were randomized to receive a placebo or an oral dose of powdered egg white daily. At 10 months, more than half of the treated children were desensitized, and at 22 months, 75% of the treated children were desensitized. None of the children receiving placebo were desensitized. After 22 months, desensitized children discontinued therapy and avoided egg for 4 to 6 weeks; of these individuals, 28% remained desensitized when retested.