RT Journal
A1 Gaziano J, Wilson PF
T1 CArdiovascular risk assessment in the 21st century
JF JAMA
JO JAMA
YR 2012
FD August 22
VO 308
IS 8
SP 816
OP 817
DO 10.1001/2012.jama.10456
UL http://dx.doi.org/10.1001/2012.jama.10456
AB 
In the 1960s, the Framingham Heart Study (FHS) investigators coined the term “factors of risk” for cardiovascular disease1; today risk factors are used routinely in daily practice to assist in risk prediction and to target prevention strategies for cardiovascular disease as well as for other diseases. The FHS investigators subsequently used risk factors to develop a multivariable model to predict the likelihood of a future coronary heart disease event. The model included several major cardiovascular risk factors that estimate the probability of developing an initial coronary disease event over the next 10 years and result in a risk score.2 This basic model is used around the globe.