RT Journal A1 Steinbrook R T1 PReexposure prophylaxis for hiv infection JF JAMA JO JAMA YR 2012 FD September 5 VO 308 IS 9 SP 865 OP 866 DO 10.1001/jama.2012.9885 UL http://dx.doi.org/10.1001/jama.2012.9885 AB On July 16, 2012, the US Food and Drug Administration (FDA) approved a daily oral antiretroviral drug to reduce the risk of sexual acquisition of human immunodeficiency virus (HIV) infection by uninfected adults.1- 2 Emtricitabine/tenofovir disoproxil fumarate (marketed by Gilead as Truvada) contains 2 nucleoside analogue HIV-1 reverse transcriptase inhibitors. Initially approved in 2004 to treat HIV infection in combination with other antiretroviral medications in people 12 years of age and older, emtricitabine/tenofovir costs about $13 900 a year in the United States for a year of treatment.