RT Journal A1 Friedrich MJ T1 SCientists investigate routing latent hiv from its reservoirs to achieve a cure JF JAMA JO JAMA YR 2012 FD July 25 VO 308 IS 4 SP 325 OP 327 DO 10.1001/jama.2012.8466 UL http://dx.doi.org/10.1001/jama.2012.8466 AB The main obstacle to wiping out HIV with ART is the reservoir of latent virus found mainly in long-lived resting memory CD4 T cells. Because these cells aren't actively replicating, the virus is both hidden from the immune system and invulnerable to ART.