RT Journal A1 Aristodemou P, Stylianides AC T1 REtinal detachment and fluoroquinolones JF JAMA JO JAMA YR 2012 FD July 18 VO 308 IS 3 SP 233 OP 233 DO 10.1001/jama.2012.6618 UL http://dx.doi.org/10.1001/jama.2012.6618 AB First, the timing of fluoroquinolone use and the treatment for a retinal detachment were very short. The association was only present for current fluoroquinolone users, not for those with recent or past use. If there was a change in the vitreous that could precipitate a retinal detachment, a retinal detachment would be expected to take some time to develop. There is usually a time lag of several days or weeks between the development of a posterior vitreous detachment and the formation of retinal breaks that may lead to a retinal detachment.2 For this reason, the association between retinal detachment and fluoroquinolone use would have been expected to hold for those with recent fluoroquinolone use as well.