RT Journal A1 Gomez-Alonso J T1 TReatment of refractory mesial temporal lobe epilepsy JF JAMA JO JAMA YR 2012 FD June 20 VO 307 IS 23 SP 2483 OP 2485 DO 10.1001/jama.2012.4987 UL http://dx.doi.org/10.1001/jama.2012.4987 AB To the Editor: The efficacy of epilepsy surgery (73% seizure-free) in the best-possible surgical candidates was corroborated by Dr Engel and colleagues.1 Their trial also showed that surgery can cause irreversible deficits because a statistically reliable decline in performance on memory tests was more frequent in the surgical group (36% in delayed recall and 55% in naming) than in the medical group (0% and 7%, respectively).1 Other aspects of the trial might deserve some clarification.