RT Journal A1 Vesper HW, Pirkle JL T1 TRans-fatty acid levels in white adults—reply JF JAMA JO JAMA YR 2012 FD June 13 VO 307 IS 22 SP 2370 OP 2371 DO 10.1001/jama.2012.5148 UL http://dx.doi.org/10.1001/jama.2012.5148 AB In Reply: More than 20 different TFAs have been reported in human blood,1- 2 and the selected 4 TFAs measured in plasma in our study are considered to be the major TFAs.3 The extent to which certain food sources affected blood levels of these 4 TFAs in our population group is not known. Although we agree that such information would be helpful for reasons such as those presented by Mr Brandt, the study did not intend to address this topic.