RT Journal A1 Mustafić H, Jouven X, Jabre P T1 EXposure to air pollutants and myocardial infarction risk—reply JF JAMA JO JAMA YR 2012 FD June 13 VO 307 IS 22 SP 2370 OP 2370 DO 10.1001/jama.2012.4118 UL http://dx.doi.org/10.1001/jama.2012.4118 AB In Reply: We agree with Mr Huang and Dr Mao that there is heterogeneity among studies evaluating the effect of air pollutants on the risk of MI. The intent in performing a meta-analysis is, as far as possible, to reduce heterogeneity. We converted the pollutant concentrations from the various studies to the same units and chose the most frequently used values for the increase in pollutant concentrations: 10 μg/m3 for all pollutants except for carbon monoxide and 1 mg/m3 for carbon monoxide. This method is frequently used for meta-analyses.1