RT Journal A1 Wang C, Huang AT T1 ELectronic health record technology—reply JF JAMA JO JAMA YR 2012 FD June 6 VO 307 IS 21 SP 2255 OP 2255 DO 10.1001/jama.2012.3530 UL http://dx.doi.org/10.1001/jama.2012.3530 AB In Reply: In response to Mr Nahass and Dr Nahass, we agree that interoperability is critical for allowing different EHR systems to connect. We see interoperability and security standards as ramps and traffic signs to entering and exiting the information highway, and key in establishing a universal database. The government or a credible agency will need to set standards with input from industry; the standards will need to be rigorously evaluated, as was done in the development of e-prescribing.1 Both proprietary and nonproprietary systems can compete for market share based on their user interface design or overall systems capability. Patents and copyright protections have been central to technological innovations; however, studies suggest that patents can also impede innovation if they are overdone.2- 3