RT Journal
A1 Hampton T
T1 REversing fragile x
JF JAMA
JO JAMA
YR 2012
FD June 6
VO 307
IS 21
SP 2247
OP 2247
DO 10.1001/jama.2012.5440
UL http://dx.doi.org/10.1001/jama.2012.5440
AB 
Individuals with FXS have a single mutation in the FMR1 gene that prevents them from producing enough of the fragile X mental retardation protein. This leads to overactivation of a cell signaling pathway involving the metabotropic glutamate receptor 5 (mGlu5).