RT Journal A1 Handsfield H T1 PRevention of oral human papillomavirus infection JF JAMA JO JAMA YR 2012 FD May 23 VO 307 IS 20 SP 2147 OP 2148 DO 10.1001/jama.2012.3566 UL http://dx.doi.org/10.1001/jama.2012.3566 AB To the Editor: Dr Schlecht's Editorial1 adds context to the report on the epidemiology of oral human papillomavirus (HPV) infection based on the National Health and Nutrition Examination Survey (NHANES).2 However, the subtitle undercuts some reassuring observations, such as the relatively low prevalence of oral HPV infection (6.9%) compared with anogenital infection and the 1% prevalence of oral HPV-16, the main type associated with oropharyngeal squamous cell carcinoma.2