RT Journal T1 STudien über experimentelle arthritiden und karditiden. ein beitrag zur frage der pathogenetischen bedeutung endokriner factoren bei dem sogenannten gelenkrheumatismus JF Journal of the American Medical Association JO Journal of the American Medical Association YR 1939 FD December 30 VO 113 IS 27 SP 2448 OP 2448 DO 10.1001/jama.1939.02800520074033 UL http://dx.doi.org/10.1001/jama.1939.02800520074033 AB This is a short monograph on the relationship between endocrine dysfunction and arthritis. The author presents a historical review of the literature on the endocrine and arthritis relationship, which he summarizes to the effect that the endocrine disturbance is either the only cause of the joint symptoms or a predisposing factor, or a coordinated one. Exclusive endocrine etiology is declined but the predisposing factor and the coordinated character are given the benefit of doubt from the review of the literature. The original work of the author is directed toward the solution of the question how far animal experiments will reveal the causal relation between endocrine disturbance and arthritic symptoms. The experiments of the author include serum and tuberculin injections, inoculation with streptococcus and polymorphodiplococcus, and foreign protein injections, applied to castrated animals as well as to controls. The conclusion of the author seems to be that the results indicate that