RT Journal
A1 Goldberg SL, Sachs A
T1 SUlfapyridine in the treatment of staphylococcus aureus bacteremia
JF Journal of the American Medical Association
JO Journal of the American Medical Association
YR 1939
FD October 28
VO 113
IS 18
SP 1639
OP 1641
DO 10.1001/jama.1939.72800430002008a
UL http://dx.doi.org/10.1001/jama.1939.72800430002008a
AB Much interest has been aroused by the advent of sulfapyridine. Although its use has been almost limited to the treatment of pneumonic processes, its efficacy in other conditions has been briefly reported.Instances of the use of the drug in staphylococcic septicemia or bacteremia of necessity are few and brief. Fenton and Hodgkiss1 reported its use in a case with an atypical clinical picture. A single culture of the blood revealed Staphylococcus aureus. The only significant finding was x-ray evidence of pleural thickening. The temperature dropped markedly twenty-four hours after administration of the drug. O'Brien and McCarthy2 reported staphylococcic bacteremia following furunculosis, with a dramatic drop in temperature and sterile blood culture following therapy with sulfapyridine. Maxwell's3 patient had staphylococcic bacteremia coincidental to pneumonia. Staphylococci were recovered from two cultures of the blood. The temperature dropped to normal in forty-eight hours and culture of the blood became