RT Journal A1 Emanuel EJ T1 PEpfar and maximizing the effects of global health assistance JF JAMA JO JAMA YR 2012 FD May 16 VO 307 IS 19 SP 2097 OP 2100 DO 10.1001/jama.2012.4989 UL http://dx.doi.org/10.1001/jama.2012.4989 AB Created by President George W. Bush in 2003, PEPFAR was, as its website says, “launched to combat HIV/AIDS.”2 The program targeted 15 “focus” countries, mostly chosen for their high rates of human immunodeficiency virus (HIV) and AIDS but also for their government's willingness to address the problems of HIV/AIDS as well as larger US geopolitical strategic reasons. PEPFAR has been the largest financial commitment of any country to global health and to treatment of any specific disease worldwide.