RT Journal A1 Webster JR T1 COst of health care and the role of physicians—reply JF JAMA JO JAMA YR 2012 FD March 28 VO 307 IS 12 SP 1253 OP 1253 DO 10.1001/jama.2012.355 UL http://dx.doi.org/10.1001/jama.2012.355 AB In Reply: Dr Baral is correct in her assessment that many improved technologies and medicines, although costly, are effective. However, the key is to use them at the right time, in the right way, and for the right patient. To use the example she cites, for patients with acute ST-segment elevation myocardial infarction, angioplasties are lifesaving, preserve heart muscle, and thus reduce the risk of future congestive heart failure, and are almost always considered appropriate.1 However, only 50% of non–acute percutaneous coronary interventions are clearly appropriate,1 representing a costly misuse of medical resources.