RT Journal
A1 Antman KH, Heitjan DF, Hortobagyi GN
T1 HIgh-dose chemotherapy for breast cancer
JF JAMA
JO JAMA
YR 1999
FD November 10
VO 282
IS 18
SP 1701
OP 1703
DO 10.1001/jama.282.18.1701
UL http://dx.doi.org/10.1001/jama.282.18.1701
AB 
While screening has resulted in a higher percentage of patients with
early stage disease and improved survival, mortality at 10 years exceed 60%
for those with 10 or more involved lymph nodes or large primary tumors. Virtually
all patients who initially present with or later develop metastatic breast
cancer ultimately die of their disease.3- 4