RT Journal
A1 Hampton T
T1 MYocardial infarction predictor
JF JAMA
JO JAMA
YR 2012
FD May 2
VO 307
IS 17
SP 1790
OP 1790
DO 10.1001/jama.2012.3997
UL http://dx.doi.org/10.1001/jama.2012.3997
AB 
Blood levels of circulating endothelial cells (CECs) may help predict an impending myocardial infarction (Damani S et al. Sci Transl Med. 2012;4[126]:126ra33). Investigators led by researchers at the Scripps Translational Science Institute, in La Jolla, Calif, found that CEC counts were significantly elevated in 50 patients who experienced an acute myocardial infarction compared with 44 controls (a median of 19 cells/mL vs 4 cells/mL). There was no correlation between CECs and typical markers of myocardial necrosis. Circulating endothelial cells from patients were also larger (with a cellular area 2.5-fold larger and a nuclear area twice that of CECs from controls).