RT Journal A1 Gordon R, Tyring S T1 VEsicular eruption JF JAMA JO JAMA YR 2012 FD April 11 VO 307 IS 14 SP 1528 OP 1529 DO 10.1001/jama.2012.436 UL http://dx.doi.org/10.1001/jama.2012.436 AB A 49-year-old man with a history of severe eczema presents to your office with slightly eroded, erythematous scaly patches on his face, chest, and back. You prescribe oral doxycycline hyclate, 150 mg/d, to avoid bacterial infection and tacrolimus ointment, 0.1%. After 5 days, he returns to your office with painful, umbilicated vesicles on his face, ears, neck and chest, and back (Figure 1). He is afebrile and denies systemic symptoms; he has no known drug allergies and denies having complications due to tetracyclines in the past. He takes no additional medications.