RT Journal
A1 Katz SJ, Morrow M
T1 THe challenge of individualizing treatments for patients with breast cancer
JF JAMA
JO JAMA
YR 2012
FD April 4
VO 307
IS 13
SP 1379
OP 1380
DO 10.1001/jama.2012.409
UL http://dx.doi.org/10.1001/jama.2012.409
AB 
One of the most complex challenges clinicians and their patients with breast cancer face is to determine a treatment plan for disease with relatively favorable prognosis. Advances in treatment have improved life expectancy, but these advances have come at a steep price because treatments impose substantial morbidity and burden on patients and their families. Concerns about the potential harm of treatments have increased as population-based screening has identified an increased number of breast cancer patients with relatively favorable prognosis.1 These concerns have motivated several initiatives to reduce morbidity and treatment burden.