RT Journal A1 Wolf AD, Volk RJ T1 REcommendations on use of prostate-specific antigen for prostate cancer screening—reply JF JAMA JO JAMA YR 2012 FD April 4 VO 307 IS 13 SP 1372 OP 1374 DO 10.1001/jama.2012.397 UL http://dx.doi.org/10.1001/jama.2012.397 AB Garnick notes that the USPSTF concluded the “routine” use of PSA for prostate cancer screening should no longer be recommended. Had that indeed been the case, we would be in general agreement with the USPSTF's recommendation. But the critical point is that the USPSTF made a D recommendation—arguing there was moderate certainty that the harms of PSA-based screening outweigh the benefits and recommending against screening altogether. We suggested the evidence supports a C recommendation, wherein men would have the opportunity to make a decision about screening in consultation with their physician. This difference is not trivial because it affirms a physician's obligation to engage men in an informed decision-making process and provide the opportunity to make an individualized decision.