RT Journal A1 Piers RD, Azoulay E, Benoit DD T1 PErceptions of appropriateness of care in the intensive care unit—reply JF JAMA JO JAMA YR 2012 FD April 4 VO 307 IS 13 SP 1370 OP 1372 DO 10.1001/jama.2012.395 UL http://dx.doi.org/10.1001/jama.2012.395 AB In Reply: Drs Nagamatsu and Yamashita suggest important possible determinants of perceptions of appropriateness of care. However, in keeping with our study's aim, we sought to collect subjective perceptions from bedside clinicians. Perceived inappropriateness of care ranged between 8% and 49% across participating countries in our study and was related to differences in the ethical environment—the worse the ethical climate, the higher the prevalence of perceptions of inappropriate care. While we acknowledge that national laws, health care structures, and other societal factors have an important influence on perceptions of appropriateness of care, as shown in the examples given by Nagamatsu and Yamashita, we believe that actual perceptions are the most important targets for efforts to improve care for patients and working environments for clinicians across nations and cultures.