RT Journal A1 Kostis JB, Cabrera J, Cheng JQ T1 LIfe expectancy after treatment for systolic hypertension—reply JF JAMA JO JAMA YR 2012 FD April 4 VO 307 IS 13 SP 1368 OP 1369 DO 10.1001/jama.2012.390 UL http://dx.doi.org/10.1001/jama.2012.390 AB Although life expectancy gain was not nominally statistically significant for all-cause mortality (P = .07), a significant gain in life expectancy was observed for all-cause mortality when patients were analyzed according to whether their systolic blood pressure was controlled to 140 mm Hg. For those controlled at this level at the end of the first year of follow-up, a gain of 333.2 days (95% CI, 186.1-484.8 days) was observed; for those controlled at 2 years of follow-up, 196.3 days (95% CI, 57.2-334.8 days) were gained; and those controlled at the end of the follow-up lived 206.4 days (95% CI, 52.5-355.7 days) longer. However, as Coca states, the primary finding of the study was a gain in life expectancy free from cardiovascular death.