RT Journal
A1 Hampton T
T1 NEw antiseizure agents
JF JAMA
JO JAMA
YR 2012
FD April 4
VO 307
IS 13
SP 1357
OP 1357
DO 10.1001/jama.2012.370
UL http://dx.doi.org/10.1001/jama.2012.370
AB 
During seizures, T-type calcium channels become active and stimulate neurons to fire at a high frequency. The new compounds, called Z941 and Z944, preferentially blocked channels responsible for high-frequency neuron firing.